报告人：Christy F. Landes教授，University of Illinois Urbana-Champaign, USA

报告时间：2025年11月27日（周四）09：00

报告地点：W210会议室

报告人简介：Christy F. Landes，现任美国伊利诺伊大学厄巴纳-香槟分校讲席教授，2003年博士毕业于美国佐治亚理工学院，之后在美国俄勒冈大学与得克萨斯大学奥斯汀分校从事博士后工作，2006-2024先后在美国休斯顿大学与莱斯大学开展工作，2023年起加入美国伊利诺伊大学厄巴纳-香槟分校，主要从事光谱仪器开发、单分子光谱、软界面动态过程的成像观测、蛋白分离、光电催化等领域研究，一直担任The Journal of Physical Chemistry Letters期刊的Senior Editor至2025年，2026年起将担任Accounts of Chemical Research期刊的Senior Editor。

报告简介：Recent efforts by our group and others have shown the promise of applying single-molecule methods to link mechanistic detail about protein adsorption to macroscale observables. When we study one molecule at a time, we eliminate ensemble averaging, thereby accessing underlying heterogeneity. However, we must develop new methods to increase information content in the resulting low density and low signal-to-noise data and to improve space and time resolution. I will highlight recent advances in super-localization microscopy for quantifying the physics and chemistry that occur between target proteins and stationary phase supports during chromatographic separations. My discussion will concentrate on the newfound ability of single-protein tracking to inform theoretical parameters by quantification of adsorption-desorption dynamics, protein unfolding, and nano-confined transport. Additionally, I will discuss using phase manipulation to encode temporal, 3D spatial, and orientational information, and briefly introduce new materials that could lead to bio-inspired active separations.